Dr Michelle Hulin
I am interested in the molecular evolution and population genetics of plant pathogenic bacteria. How have bacteria evolved to manipulate the plant immune system and what genetic diversity exists in plant-associated bacterial populations, that can be acted upon by selection. My PhD project (completed at NIAB-EMR/University of Reading, March 2017) focused on determining the genetic basis of host specificity of P. syringae on Prunus species. This involved comparative genomics to identify key factors in disease, followed by molecular plant pathology to determine their role in this interaction.
My current research is continuing on from my PhD, with the eventual aim to identify novel sources of host resistance based on the knowledge of factors that are vital for pathogenicity. I am also keen to apply some of the bioinformatics and molecular techniques optimised during my PhD to other bacterial diseases of perennial hosts.
- Hulin M.T., Mansfield J.W., Brian, P., Xu, X., Jackson R.W. and Harrison R.J.. (2018). Characterisation of the pathogenicity of strains of Pseudomonas syringae towards cherry and plum. Plant Pathology. Accepted article online. DOI: 10.1111/ppa.12834.
- Hulin MT, Armitage AD, Vicente JG, Holub EB, Baxter L, Bates HJ, Mansfield JW, Jackson RW, Harrison RJ. (2018). Comparative genomics of Pseudomonas syringae reveals convergent gene gain and loss associated with specialization onto cherry (Prunus avium). New Phytologist, doi: 10.1111/nph.15182.
- Li B, Hulin M.T., Brain P, Mansfield J.W., Jackson R.W. and Harrison R.J. . (2015). Rapid, automated detection of stem canker symptoms in woody perennials using artificial neural network analysis Plant Methods 11:. 57.
- Hulin, M.,Harrison, E., Stratford, M. and Wheals, A.E., . (2014). Rapid identification of the genus Dekkera/Brettanomyces, the Dekkera subgroup and all individual species. International Journal of Food Microbiology, 187. 7-14.
- Hulin, M. and Wheals, A., . (2014). Rapid identification of Zygosaccharomyces with genus-specific primers International Journal of Food Microbiology, 173. 9-13.
- Sharpe, B., Hulin, M., Thorne-Wallis, J. and Wheals, A., . (2014). Synteny analysis provides a route to design genus-specific PCR primers for rapid identification of all Saccharomyces species FEMS Yeast Research, 14 (3). 517-525.