Dr Edward Dobbs
My main research interest is in viral infection in the cultivated common white mushroom (Agaricus bisporus). I am in the 3rd year of my first post-doctoral position where I am using molecular techniques coupled with Next Generation Sequencing to develop tests for viruses in mushrooms. This is an EU-funded collaboration with fellow scientists in Dublin (Teagasc), Armagh (AFBI), Wageningen in the Netherlands (PRI) and Rumbeke in Belgium (Inagro) in which we are investigating the epidemiology and control of two mushroom pathogens Mushroom Virus X (MVX) and Trichoderma. If you are interested in our projects then please visit: www.mushtv.eu
MVX is a serious challenge to the mushroom cultivation industry in Europe as it has resulted in farms closures in the UK in the late 1990s and early 2000s. MVX is a complex of numerous viruses and the best way to understand their biology is to fully sequence them. I have now completed the genome sequencing and I am currently characterising the viruses in order to understand their individual roles in the complex. I have also been developing RNA extraction methods to extract clean, stable RNA from both mushrooms and mushroom compost. The viral genomes and extraction methods will allow development of tests to detect the viruses in compost before it is used by growers, which should enhance the security and reliability of the industry.
I am also interested in using my knowledge of viruses, epigenetics, new technologies and molecular biology to develop new areas of research in horticultural crops.
- Nicholas Rhind, Zehua Chen, Moran Yassour, Dawn A. Thompson, Brian J. Haas, Naomi Habib, Ilan Wapinski, Sushmita Roy, Michael F. Lin, David I. Heiman, Sarah K. Young, Kanji Furuya, Yabin Guo, Alison Pidoux, Huei Mei Chen, Barbara Robbertse, Jonathan M. Goldberg, Keita Aoki, Elizabeth H. Bayne, Aaron M. Berlin, Christopher A. Desjardins, Edward Dobbs, Livio Dukaj, Lin Fan, Michael G. FitzGerald, Courtney French, Sharvari Gujja, Klavs Hansen, Dan Keifenheim, Joshua Z. Levin, Rebecca A. Mosher, Carolin A. Müller, Jenna Pfiffner, Margaret Priest, Carsten Russ, Agata Smialowska, Peter Swoboda, Sean M. Sykes, Matthew Vaughn, Sonya Vengrova, Ryan Yoder, Qiandong Zeng, Robin Allshire, David Baulcombe, Bruce W. Birren, William Brown, Karl Ekwall, Manolis Kellis, Janet Leatherwood, Henry Levin, Hanah Margalit, Rob Martienssen, Conrad A. Nieduszynski, Joseph W. Spatafora, Nir Friedman, Jacob Z. Dalgaard, Peter Baumann, Hironori Niki, Aviv Regev, Chad Nusbaum. (2011). Comparative Functional Genomics of the Fission Yeasts. Science: Vol. 332 no. 6032 . pp. 930-936 DOI: 10.1126/science.1203357 .